产品名称
HCN3 Rabbit Polyclonal Antibody
蛋白名称
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
Q9P1Z3
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q9P1Z3/entry
Mouse Swissprot No.
O88705
Mouse Swissprot Link
http://www.uniprot.org/uniprot/O88705
Rat Swissprot Link
http://www.uniprot.org/uniprot/O54941Q9JKA8
免疫原
Synthesized peptide derived from human protein . at AA range: 150-230
特异性
HCN3 Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a multi-pass membrane protein that functions as a voltage gated cation channel. The encoded protein is a member of a family of closely related cyclic adenosine monophosphate-binding channel proteins. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012],
细胞定位
Cell membrane ; Multi-pass membrane protein .
功能
domain:The segment S4 is probably the voltage-sensor and is characterized by a series of positively charged amino acids at every third position.,function:Putative hyperpolarization-activated ion channel exhibiting weak selectivity for potassium over sodium ions.,similarity:Belongs to the potassium channel HCN family.,similarity:Contains 1 cyclic nucleotide-binding domain.,subunit:The potassium channel is probably composed of a homo- or heterotetrameric complex of pore-forming subunits.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
