产品名称
EIF2A/CDA02 Rabbit Polyclonal Antibody
基因名称
EIF2A CDA02 MSTP004 MSTP089
蛋白名称
Eukaryotic translation initiation factor 2A (eIF-2A) (65 kDa eukaryotic translation initiation factor 2A)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=83939
Human Swissprot No.
Q9BY44
Human Swissprot Link
https://www.uniprot.org/uniprot/Q9BY44
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=229317
Mouse Swissprot No.
Q8BJW6
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q8BJW6/entry
特异性
This antibody detects endogenous levels of EIF2A/CDA02 at Human, Mouse
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
组织表达
Widely expressed. Expressed at higher level in pancreas, heart, brain and placenta.
功能
Functions in the early steps of protein synthesis of a small number of specific mRNAs. Acts by directing the binding of methionyl-tRNAi to 40S ribosomal subunits. In contrast to the eIF-2 complex, it binds methionyl-tRNAi to 40S subunits in a codon-dependent manner, whereas the eIF-2 complex binds methionyl-tRNAi to 40S subunits in a GTP-dependent manner.