产品名称
IFT140 Rabbit Polyclonal Antibody
基因名称
IFT140 KIAA0590 WDTC2
蛋白名称
Intraflagellar transport protein 140 homolog (WD and tetratricopeptide repeats protein 2)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=9742
Human Swissprot No.
Q96RY7
Human Swissprot Link
https://www.uniprot.org/uniprot/Q96RY7
特异性
This antibody detects endogenous levels of IFT140 at Human
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
细胞定位
Cytoplasm, cytoskeleton, cilium basal body . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Cell projection, cilium .
功能
Component of the IFT complex A (IFT-A), a complex required for retrograde ciliary transport and entry into cilia of G protein-coupled receptors (GPCRs) . Plays a pivotal role in proper development and function of ciliated cells through its role in ciliogenesis and/or cilium maintenance . Required for the development and maintenance of the outer segments of rod and cone photoreceptor cells. Plays a role in maintenance and the delivery of opsin to the outer segment of photoreceptor cells (By similarity).