产品名称
IFT88 Rabbit Polyclonal Antibody
蛋白名称
Intraflagellar transport protein 88 homolog (Recessive polycystic kidney disease protein Tg737 homolog) (Tetratricopeptide repeat protein 10) (TPR repeat protein 10)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=8100
Human Swissprot No.
Q13099
Human Swissprot Link
https://www.uniprot.org/uniprot/Q13099
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=21821
Mouse Swissprot No.
Q61371
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q61371/entry
特异性
This antibody detects endogenous levels of IFT88 at Human, Mouse
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
组织表达
Expressed in the heart, brain, liver, lung, kidney, skeletal muscle and pancreas.
细胞定位
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole . Cell projection, cilium . Cytoplasm, cytoskeleton, cilium basal body . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Cytoplasm . Cell projection, cilium, flagellum . Colocalizes with ENTR1 and gamma-tubulin at the basal body of primary cilia. Colocalizes with ENTR1 and pericentrin at the centrosome. .
功能
Involved in primary cilium biogenesis. Also involved in autophagy since it is required for trafficking of ATG16L and the expansion of the autophagic compartment.
