产品名称
CRHR2 (PTR1205) Mouse Monoclonal Antibody
蛋白名称
Corticotropin-releasing factor receptor 2 (CRF-R-2) (CRF-R2) (CRFR-2) (Corticotropin-releasing hormone receptor 2) (CRH-R-2) (CRH-R2)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=1395
Human Swissprot No.
Q13324
Human Swissprot Link
https://www.uniprot.org/uniprot/Q13324
Mouse Swissprot No.
Q60748
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q60748/entry
特异性
This antibody detects endogenous levels of CRHR2 at Human, Predict react with Mouse, Rat
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
细胞定位
Cell membrane ; Multi-pass membrane protein .
功能
G-protein coupled receptor for CRH (corticotropin-releasing factor), UCN (urocortin), UCN2 and UCN3. Has high affinity for UCN. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and down-stream effectors, such as adenylate cyclase. Promotes the activation of adenylate cyclase, leading to increased intracellular cAMP levels.
