产品名称
p15 INK (PTR2192) Mouse Monoclonal Antibody
蛋白名称
Cyclin-dependent kinase 4 inhibitor B (Multiple tumor suppressor 2) (MTS-2) (p14-INK4b) (p15-INK4b) (p15INK4B)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=1030
Human Swissprot No.
P42772
Human Swissprot Link
https://www.uniprot.org/uniprot/P42772
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=12579
Mouse Swissprot No.
P55271
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/P55271/entry
特异性
This antibody detects endogenous levels of p15 INK (PTR2192) at Human. The antibody was also Predict react with Mouse;Rat
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
组织表达
Isoform 2 is expressed in normal (keratinocytes, fibroblasts) and tumor cell lines.
细胞定位
Cytoplasm . Also found in the nucleus.
功能
Interacts strongly with CDK4 and CDK6. Potent inhibitor. Potential effector of TGF-beta induced cell cycle arrest.
