产品名称
ERP27 (9F7) Rabbit Monoclonal Antibody
别名
C12orf46; ERp27; PDIA8;
纯度
Affinity-chromatography
存储缓冲液
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
Human Swissprot No.
Q96DN0
稀释度
WB 1:500~1:2000 IHC 1:50~1:200 ICC/IF 1:50~1:200
注意事项
ERP27 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
细胞定位
Endoplasmic reticulum lumen
功能
Specifically binds unfolded proteins and may recruit protein disulfide isomerase PDIA3 to unfolded substrates (PubMed:
16940051, PubMed:
23192347). Binds protein substrates via a hydrophobic pocket in the C-terminal domain (PubMed:
16940051, PubMed:
23192347). May play a role in the unfolded stress response (PubMed:
23192347).