产品名称
LAP3 (6I12) Rabbit Monoclonal Antibody
别名
LAP; Lap3; LAPEP; Leucine aminopeptidase 3; PEPS; Peptidase S;
纯度
Affinity-chromatography
存储缓冲液
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
Human Swissprot No.
P28838
稀释度
WB 1:500~1:2000 IHC 1:50~1:200
注意事项
LAP3 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
细胞定位
Cytoplasm {ECO:0000250|UniProtKB:Q68FS4}.
功能
Cytolosic metallopeptidase that catalyzes the removal of unsubstituted N-terminal hydrophobic amino acids from various peptides. The presence of Zn(2+) ions is essential for the peptidase activity, and the association with other cofactors can modulate the substrate spectificity of the enzyme. For instance, in the presence of Mn(2+), it displays a specific Cys-Gly hydrolyzing activity of Cys-Gly-S- conjugates. Involved in the metabolism of glutathione and in the degradation of glutathione S-conjugates, which may play a role in the control of the cell redox status.