产品名称
Ceruloplasmin (10V12) Rabbit Monoclonal Antibody
别名
Ceruloplasmin; CP2; Ferroxidase;
纯度
Affinity-chromatography
存储缓冲液
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
Human Swissprot No.
P00450
注意事项
Ceruloplasmin Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
组织表达
Expressed by the liver and secreted in plasma.
细胞定位
Secreted. Note=Colocalizes with GCP1 in secretory intracellular compartments.
功能
Ceruloplasmin is a blue, copper-binding (6-7 atoms per molecule) glycoprotein. It has ferroxidase activity oxidizing Fe(2+) to Fe(3+) without releasing radical oxygen species. It is involved in iron transport across the cell membrane. Provides Cu(2+) ions for the ascorbate-mediated deaminase degradation of the heparan sulfate chains of GPC1. May also play a role in fetal lung development or pulmonary antioxidant defense (By similarity).
