产品名称
Desmocollin 1 (17F10) Rabbit Monoclonal Antibody
纯度
Affinity-chromatography
存储缓冲液
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
Human Swissprot No.
Q08554
注意事项
Desmocollin 1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
组织表达
Strongly expressed in epidermis, less in lymph node and tongue
细胞定位
Cell membrane; Single-pass type I membrane protein. Cell junction, desmosome
功能
Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. May contribute to epidermal cell positioning (stratification) by mediating differential adhesiveness between cells that express different isoforms. Linked to the keratinization of epithelial tissues.
