RM7113

Lunatic Fringe (6M18) Rabbit Monoclonal Antibody

SCDO3;

Affinity-chromatography

常规抗体

LFNG

WB

Human,Mouse,Rat

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

3955

Q8NES3

WB 1:500~1:2000

42kDa

Rabbit IgG

Lunatic Fringe Antibody is for research use only and not for use in diagnostic or therapeutic procedures.

Golgi apparatus membrane; Single- pass type II membrane protein

Glycosyltransferase that initiates the elongation of O-linked fucose residues attached to EGF-like repeats in the extracellular domain of Notch molecules. Modulates NOTCH1 activity by modifying O- fucose residues at specific EGF-like domains resulting in inhibition of NOTCH1 activation by JAG1 and enhancement of NOTCH1 activation by DLL1 via an increase in its binding to DLL1 (By similarity). Decreases the binding of JAG1 to NOTCH2 but not that of DLL1 (PubMed:11346656). Essential mediator of somite segmentation and patterning (By similarity).

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