RM7108

PDGF B (1X19) Rabbit Monoclonal Antibody

PDGF2; Pdgfb; Platelet derived growth factor 2; Platelet derived growth factor B chain; Platelet derived growth factor beta; SIS; SSV;

Affinity-chromatography

常规抗体

PDGFB

PDGF2, SIS

WB

Human,Mouse,Rat

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% New type preservative N and 0.05% BSA.

5155

P01127

A synthetic peptide of human PDGF B

WB: 1:1000 IHC: 1:20

27kDa

27kDa

Rabbit IgG

PDGF B Antibody is for research use only and not for use in diagnostic or therapeutic procedures.

Expressed at high levels in the heart, brain (sustantia nigra), placenta and fetal kidney. Expressed at moderate levels in the brain (hippocampus), skeletal muscle, kidney and lung

Secreted. Note=Released by platelets upon wounding

Growth factor that plays an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival and chemotaxis. Potent mitogen for cells of mesenchymal origin (PubMed:26599395). Required for normal proliferation and recruitment of pericytes and vascular smooth muscle cells in the central nervous system, skin, lung, heart and placenta. Required for normal blood vessel development, and for normal development of kidney glomeruli. Plays an important role in wound healing. Signaling is modulated by the formation of heterodimers with PDGFA (By similarity).

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