产品名称
SEC14L2 / TAP (5M6) Rabbit Monoclonal Antibody
别名
hTAP; SEC14 like 2; Sec14l2; SPF; Squalene transfer protein; TAP; TAP1;
纯度
Affinity-chromatography
蛋白名称
C22orf6, KIAA1186, KIAA1658
存储缓冲液
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
Human Swissprot No.
O76054
稀释度
WB 1:500~1:2000 IHC 1:50~1:200
注意事项
SEC14L2 / TAP Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
组织表达
Widely expressed. Strong expression in liver, brain and prostate.
细胞定位
Cytoplasm. Nucleus. Note=Cytoplasmic in absence of alpha-tocopherol, and nuclear in presence of alpha-tocopherol
功能
Carrier protein. Binds to some hydrophobic molecules and promotes their transfer between the different cellular sites. Binds with high affinity to alpha-tocopherol. Also binds with a weaker affinity to other tocopherols and to tocotrienols. May have a transcriptional activatory activity via its association with alpha- tocopherol. Probably recognizes and binds some squalene structure, suggesting that it may regulate cholesterol biosynthesis by increasing the transfer of squalene to a metabolic active pool in the cell.
