RM7101

HN1 (11K13) Rabbit Monoclonal Antibody

ARM2; HN1; HN1A;

Affinity-chromatography

常规抗体

JPT1

WB

Human,Mouse,Rat

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

51155

Q9UK76

WB 1:500~1:2000 FC 1:50

16kDa

Rabbit IgG

HN1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.

Expressed in testis, skeletal muscle, thymus, prostate, colon, peripheral blood cells, brain and placenta

Nucleus. Cytoplasm

Modulates negatively AKT-mediated GSK3B signaling (PubMed:21323578, PubMed:22155408). Induces CTNNB1 'Ser-33' phosphorylation and degradation through the suppression of the inhibitory 'Ser-9' phosphorylation of GSK3B, which represses the function of the APC:CTNNB1:GSK3B complex and the interaction with CDH1/E-cadherin in adherent junctions (PubMed:25169422). Plays a role in the regulation of cell cycle and cell adhesion (PubMed:25169422, PubMed:25450365). Has an inhibitory role on AR-signaling pathway through the induction of receptor proteosomal degradation (PubMed:22155408).

现货