RM7061

TCEB2 (14Y17) Rabbit Monoclonal Antibody

EloB; Elongin B; SIII; SIII p18; Tceb2;

Affinity-chromatography

常规抗体

ELOB

TCEB2

WB

Human

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

6923

Q15370

WB 1:500~1:2000

13kDa

Rabbit IgG

TCEB2 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.

Nucleus.

SIII, also known as elongin, is a general transcription elongation factor that increases the RNA polymerase II transcription elongation past template-encoded arresting sites. Subunit A is transcriptionally active and its transcription activity is strongly enhanced by binding to the dimeric complex of the SIII regulatory subunits B and C (elongin BC complex) (PubMed:7638163). In embryonic stem cells, the elongin BC complex is recruited by EPOP to Polycomb group (PcG) target genes in order generate genomic region that display both active and repressive chromatin properties, an important feature of pluripotent stem cells (By similarity).

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