产品名称
TCTEX1 (7I4) Rabbit Monoclonal Antibody
别名
AGS2; DYNLT1; TCTEL1; Tctex1;
纯度
Affinity-chromatography
蛋白名称
TCTEL1, TCTEX-1, TCTEX1
存储缓冲液
Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% New type preservative N and 0.05% BSA.
Human Swissprot No.
P63172
免疫原
Recombinant protein of human TCTEX-1
稀释度
WB: 1:1000 IHC: 1:20 ICC/IF: 1:100 FC: 1:20 IP: 1:20
注意事项
TCTEX1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
组织表达
Expressed in heart, placenta, skeletal muscle kidney, pancreas, spleen, prostate, testis, ovary, ileum and colon Expressed in lung endothelial and smooth muscle cells (at protein level).
细胞定位
Golgi apparatus. Cytoplasm. Cytoplasm, cytoskeleton, spindle Note=Localizes to mitotic spindles.
功能
Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. Binds to transport cargos and is involved in apical cargo transport such as rhodopsin-bearing vesicles in polarized epithelia. May also be a accessory component of axonemal dynein. (Microbial infection) Is involved in intracellular targeting of D-type retrovirus gag polyproteins to the cytoplasmic assembly site.
