产品名称
NSDHL (19N2) Rabbit Monoclonal Antibody
别名
NSDHL; SDR31E1; XAP104;
纯度
Affinity-chromatography
存储缓冲液
Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% New type preservative N and 0.05% BSA.
Human Swissprot No.
Q15738
免疫原
A synthetic peptide of human NSDHL
注意事项
NSDHL Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
组织表达
Brain, heart, liver, lung, kidney, skin and placenta
细胞定位
Endoplasmic reticulum membrane; Single-pass membrane protein. Lipid droplet {ECO:0000250|UniProtKB:Q9R1J0} Note=Trafficking through the Golgi is necessary for ER membrane localization. {ECO:0000250|UniProtKB:Q9R1J0}
功能
Catalyzes the NAD(P)(+)-dependent oxidative decarboxylation of the C4 methyl groups of 4-alpha-carboxysterols in post-squalene cholesterol biosynthesis (By similarity). Plays also a role in the regulation of the endocytic trafficking of EGFR (By similarity).