产品名称
CRCP (1Y6) Rabbit Monoclonal Antibody
别名
CGRPRCP; CRCP; HsC17; RCP; RCP9;
纯度
Affinity-chromatography
存储缓冲液
Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% New type preservative N and 0.05% BSA.
Human Swissprot No.
O75575
免疫原
A synthetic peptide of human CRCP
稀释度
WB: 1:1000 IHC: 1:50 ICC/IF: 1:50 IP: 1:20
注意事项
CRCP Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
组织表达
Ubiquitous. Most prevalent in testis.
细胞定位
Nucleus. Cell membrane; Peripheral membrane protein; Cytoplasmic side
功能
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. Plays a key role in sensing and limiting infection by intracellular bacteria and DNA viruses. Acts as nuclear and cytosolic DNA sensor involved in innate immune response. Can sense non-self dsDNA that serves as template for transcription into dsRNA. The non-self RNA polymerase III transcripts induce type I interferon and NF- Kappa-B through the RIG-I pathway (By similarity).
