产品名称
PLTP Rabbit Polyclonal Antibody
蛋白名称
Phospholipid transfer protein (Lipid transfer protein II)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
P55058
Human Swissprot Link
https://www.uniprot.org/uniprotkb/P55058/entry
Mouse Swissprot No.
P55065
Mouse Swissprot Link
http://www.uniprot.org/uniprot/P55065
免疫原
Synthesized peptide derived from human protein . at AA range: 180-260
特异性
PLTP Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
The protein encoded by this gene is one of at least two lipid transfer proteins found in human plasma. The encoded protein transfers phospholipids from triglyceride-rich lipoproteins to high density lipoprotein (HDL). In addition to regulating the size of HDL particles, this protein may be involved in cholesterol metabolism. At least two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],
组织表达
Widely expressed. Highest level of expression in the ovary, thymus and placenta, with moderate levels found in the pancreas, small intestine, testis, lung and prostrate. Low level expression in the kidney, liver and spleen, with very low levels found in the heart, colon, skeletal muscle, leukocytes and brain. Expressed in the cortical neurons.
细胞定位
Secreted . Nucleus . Nuclear export is XPO1/CRM1-dependent. .
功能
function:Converts HDL into larger and smaller particles. May play a key role in extracellular phospholipid transport and modulation of hdl particles.,similarity:Belongs to the BPI/LBP/Plunc superfamily. BPI/LBP family.,tissue specificity:Wide tissue distribution. Placenta > pancreas > lung > kidney > heart > liver > skeletal muscle > brain.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
