产品名称
TMEM43 (2M3) Rabbit Monoclonal Antibody
别名
ARVC5; ARVD5; EDMD7; LUMA; Tmem43; Transmembrane protein 43;
纯度
Affinity-chromatography
存储缓冲液
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
Human Swissprot No.
Q9BTV4
稀释度
WB 1:500~1:2000 IHC 1:50~1:200
注意事项
TMEM43 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
组织表达
Highest expression in placenta. Also found at lower levels in heart, ovary, spleen, small intestine, thymus, prostate and testis.
细胞定位
Endoplasmic reticulum. Nucleus inner membrane; Multi-pass membrane protein. Note=Retained in the inner nuclear membrane through interaction with EMD and A- and B-lamins. The N- and C-termini are oriented towards the nucleoplasm. The majority of the hydrophilic domain resides in the endoplasmic reticulum lumen (By similarity).
功能
May have an important role in maintaining nuclear envelope structure by organizing protein complexes at the inner nuclear membrane. Required for retaining emerin at the inner nuclear membrane (By similarity).
