产品名称
UFC1 (2U18) Rabbit Monoclonal Antibody
别名
HSPC155; Ubiquitin fold modifier conjugating enzyme 1; UFC1; Ufm1 conjugating enzyme 1;
纯度
Affinity-chromatography
基因名称
UFC1 {ECO:0000303|PubMed:15071506, ECO:0000312|HGNC:HGNC:26941}
存储缓冲液
Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% New type preservative N and 0.05% BSA.
Human Swissprot No.
Q9Y3C8
免疫原
Recombinant protein of human UFC1
稀释度
WB: 1:2000-1:10000 IHC: 1:20
注意事项
UFC1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
功能
E1-like enzyme which specifically catalyzes the second step in ufmylation (PubMed:
15071506, PubMed:
29868776). Accepts the ubiquitin-like modifier UFM1 from the E1 enzyme UBA5 and forms an intermediate with UFM1 via a thioester linkage (PubMed:
15071506, PubMed:
29868776). Ufmylation is involved in reticulophagy (also called ER-phagy) induced in response to endoplasmic reticulum stress (PubMed:
32160526).
