RM6996

TNFAIP8 (12V16) Rabbit Monoclonal Antibody

NDED; SCCS2; TNFAIP8;

Affinity-chromatography

常规抗体

TNFAIP8

WB

Human

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% New type preservative N and 0.05% BSA.

25816

O95379

A synthetic peptide of human TNFAIP8

WB: 1:1000 IP: 1:20

21-23kDa

23kDa

Rabbit IgG

TNFAIP8 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.

Expressed at high levels in the spleen, lymph node, thymus, thyroid, bone marrow and placenta. Expressed at high levels both in various tumor tissues, unstimulated and cytokine-activated cultured cells. Expressed at low levels in the spinal cord, ovary, lung, adrenal glands, heart, brain, testis and skeletal muscle

Cytoplasm.

Acts as a negative mediator of apoptosis and may play a role in tumor progression. Suppresses the TNF-mediated apoptosis by inhibiting caspase-8 activity but not the processing of procaspase-8, subsequently resulting in inhibition of BID cleavage and caspase-3 activation.

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