产品名称
PCBP2 (1A19) Rabbit Monoclonal Antibody
别名
Alpha CP2; Cbp; CTBP; hnRNP E2; Hnrnpx; HNRPE2; Hnrpx; PCBP2;
纯度
Affinity-chromatography
存储缓冲液
Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% New type preservative N and 0.05% BSA.
Human Swissprot No.
Q15366
免疫原
A synthetic peptide of human PCBP2
稀释度
WB: 1:1000 IHC: 1:100 ICC/IF: 1:100 FC: 1:50 IP: 1:20
注意事项
PCBP2 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
组织表达
Detected in all tissues examined.
细胞定位
Nucleus. Cytoplasm. Note=Loosely bound in the nucleus. May shuttle between the nucleus and the cytoplasm
功能
Single-stranded nucleic acid binding protein that binds preferentially to oligo dC. Major cellular poly(rC)-binding protein. Binds also poly(rU). Negatively regulates cellular antiviral responses mediated by MAVS signaling (PubMed:
19881509). It acts as an adapter between MAVS and the E3 ubiquitin ligase ITCH, therefore triggering MAVS ubiquitination and degradation (PubMed:
19881509).
