产品名称
AZI2 (15T16) Rabbit Monoclonal Antibody
别名
AZ2; AZI2; Nak associated protein 1; NAP1; TILP;
纯度
Affinity-chromatography
存储缓冲液
Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% New type preservative N and 0.05% BSA.
Human Swissprot No.
Q9H6S1
免疫原
Recombinant protein of human AZI2
稀释度
WB: 1:1000-1:5000 IHC: 1:20 ICC/IF: 1:20
注意事项
AZI2 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
组织表达
Widely expressed. Abundant expression seen in the pancreas and testis.
功能
Adapter protein which binds TBK1 and IKBKE playing a role in antiviral innate immunity. Activates serine/threonine-protein kinase TBK1 and facilitates its oligomerization. Enhances the phosphorylation of NF-kappa-B p65 subunit RELA by TBK1. Promotes TBK1-induced as well as TNF-alpha or PMA-induced activation of NF-kappa-B. Participates in IFNB promoter activation via TICAM1.