产品名称
PCBP2 (1A19) Rabbit Monoclonal Antibody
别名
Alpha CP2; Cbp; CTBP; hnRNP E2; Hnrnpx; HNRPE2; Hnrpx; PCBP2;
纯度
Affinity-chromatography
存储缓冲液
Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% New type preservative N and 0.05% BSA.
Human Swissprot No.
Q15366
免疫原
A synthetic peptide of human PCBP2
注意事项
PCBP2 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
组织表达
Detected in all tissues examined.
细胞定位
Nucleus. Cytoplasm. Note=Loosely bound in the nucleus. May shuttle between the nucleus and the cytoplasm
功能
Single-stranded nucleic acid binding protein that binds preferentially to oligo dC. Major cellular poly(rC)-binding protein. Binds also poly(rU). Negatively regulates cellular antiviral responses mediated by MAVS signaling (PubMed:
19881509). It acts as an adapter between MAVS and the E3 ubiquitin ligase ITCH, therefore triggering MAVS ubiquitination and degradation (PubMed:
19881509).
