产品名称
IFT88 (5Y14) Rabbit Monoclonal Antibody
别名
DAF19; hTg737; Ift88; TG737; TTC10;
纯度
Affinity-chromatography
存储缓冲液
Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% New type preservative N and 0.05% BSA.
Human Swissprot No.
Q13099
免疫原
A synthetic peptide of human IFT88
稀释度
WB: 1:2000-1:10000 FC: 1:50
注意事项
IFT88 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
组织表达
Expressed in the heart, brain, liver, lung, kidney, skeletal muscle and pancreas.
细胞定位
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole {ECO:0000250|UniProtKB:Q61371}. Cell projection, cilium. Cytoplasm, cytoskeleton, cilium basal body. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm {ECO:0000250|UniProtKB:Q61371}. Cell projection, cilium, flagellum {ECO:0000250|UniProtKB:Q61371}. Note=Colocalizes with ENTR1 and gamma- tubulin at the basal body of primary cilia. Colocalizes with ENTR1 and pericentrin at the centrosome.
功能
Involved in primary cilium biogenesis. Also involved in autophagy since it is required for trafficking of ATG16L and the expansion of the autophagic compartment.
