产品名称
PSMC5 (17I3) Rabbit Monoclonal Antibody
别名
Cim3; p45; p45/SUG; PSMC5; Rpt6; SUG1; TBP10; TRIP1;
纯度
Affinity-chromatography
存储缓冲液
Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% New type preservative N and 0.05% BSA.
Human Swissprot No.
P62195
免疫原
A synthetic peptide of human PSMC5
稀释度
WB: 1:2000-1:10000 IHC: 1:20 ICC/IF: 1:50 FC: 1:20-1:100 IP: 1:20
注意事项
PSMC5 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
功能
Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair. PSMC5 belongs to the heterohexameric ring of AAA (ATPases associated with diverse cellular activities) proteins that unfolds ubiquitinated target proteins that are concurrently translocated into a proteolytic chamber and degraded into peptides.