产品名称
PCTAIRE1 (12O9) Rabbit Monoclonal Antibody
别名
Cdk16; PCTAIRE; PCTAIRE1; PCTGAIRE; PCTK1;
纯度
Affinity-chromatography
存储缓冲液
Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% New type preservative N and 0.05% BSA.
Human Swissprot No.
Q00536
免疫原
Recombinant protein of human PCTAIRE1
注意事项
PCTAIRE1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
组织表达
Detected in pancreas islets (at protein level). Detected in brain and pancreas.
细胞定位
Cytoplasm. Cytoplasmic vesicle, secretory vesicle. Cell membrane; Peripheral membrane protein; Cytoplasmic side Cell junction, synapse, synaptosome. Note=Colocalizes with insulin in pancreas islets. Recruited to the cell membrane by CCNY
功能
Protein kinase that plays a role in vesicle-mediated transport processes and exocytosis. Regulates GH1 release by brain neurons. Phosphorylates NSF, and thereby regulates NSF oligomerization. Required for normal spermatogenesis. Regulates neuron differentiation and dendrite development (By similarity). Plays a role in the regulation of insulin secretion in response to changes in blood glucose levels. Can phosphorylate CCNY at 'Ser-336' (in vitro).
