产品名称
Nup107 (5E5) Rabbit Monoclonal Antibody
纯度
Affinity-chromatography
存储缓冲液
Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% New type preservative N and 0.05% BSA.
Human Swissprot No.
P57740
免疫原
A synthetic peptide of human Nup107
注意事项
Nup107 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
组织表达
Ubiquitously expressed in fetal and adult tissues.
细胞定位
Nucleus membrane. Nucleus, nuclear pore complex. Chromosome, centromere, kinetochore. Note=Located on both the cytoplasmic and nuclear sides of the NPC core structure (PubMed:11564755). During mitosis, localizes to the kinetochores (PubMed:11564755). Dissociates from the dissasembled NPC structure late during prophase of mitosis (PubMed:11564755)
功能
Plays a role in the nuclear pore complex (NPC) assembly and/or maintenance (PubMed:
12552102, PubMed:
15229283, PubMed:
30179222). Required for the assembly of peripheral proteins into the NPC (PubMed:
15229283, PubMed:
12552102). May anchor NUP62 to the NPC (PubMed:
15229283). Involved in nephrogenesis (PubMed:
30179222).