产品名称
PGK2 Rabbit Polyclonal Antibody
蛋白名称
Phosphoglycerate kinase 2 (EC 2.7.2.3) (Phosphoglycerate kinase, testis specific)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
P07205
Human Swissprot Link
https://www.uniprot.org/uniprotkb/P07205/entry
Mouse Swissprot No.
P09041
Mouse Swissprot Link
http://www.uniprot.org/uniprot/P09041
免疫原
Synthesized peptide derived from human protein . at AA range: 80-160
特异性
PGK2 Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
phosphoglycerate kinase 2(PGK2) Homo sapiens This gene is intronless, arose via retrotransposition of the phosphoglycerate kinase 1 gene, and is expressed specifically in the testis. Initially assumed to be a pseudogene, the encoded protein is actually a functional phosphoglycerate kinase that catalyzes the reversible conversion of 1,3-bisphosphoglycerate to 3-phosphoglycerate, during the Embden-Meyerhof-Parnas pathway of glycolysis, in the later stages of spermatogenesis.[provided by RefSeq, May 2010],
组织表达
Mainly found in round spermatids. Localized on the principle piece in the sperm (at protein level). Testis-specific. Expression significantly decreased in the testis of elderly men.
信号通路
Glycolysis / Gluconeogenesis;
功能
catalytic activity:ATP + 3-phospho-D-glycerate = ADP + 3-phospho-D-glyceroyl phosphate.,online information:Phosphoglycerate kinase entry,pathway:Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 2/5.,similarity:Belongs to the phosphoglycerate kinase family.,subunit:Monomer.,tissue specificity:Testis specific.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
