RM6935

SFT (10Q11) Rabbit Monoclonal Antibody

SFT; UBC4/5; UbcH5; UBCH5A; Ube2d1;

Affinity-chromatography

常规抗体

UBE2D1

SFT, UBC5A, UBCH5, UBCH5A

WB

Human,Mouse,Rat

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% New type preservative N and 0.05% BSA.

7321

P51668

A synthetic peptide of human SFT

WB: 1:2000-1:10000 IHC: 1:20 FC: 1:20 IP: 1:20

17kDa

17kDa

Rabbit IgG

SFT Antibody is for research use only and not for use in diagnostic or therapeutic procedures.

Ubiquitous. Up-regulated in livers of iron- overloaded patients with hereditary hemochromatosis

Cytoplasm.

Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins (PubMed:22496338). In vitro catalyzes 'Lys-48'-linked polyubiquitination (PubMed:20061386). Mediates the selective degradation of short-lived and abnormal proteins. Functions in the E6/E6-AP-induced ubiquitination of p53/TP53. Mediates ubiquitination of PEX5 and auto-ubiquitination of STUB1, TRAF6 and TRIM63/MURF1 (PubMed:18042044, PubMed:18359941). Ubiquitinates STUB1-associated HSP90AB1 in vitro (PubMed:18042044). Lacks inherent specificity for any particular lysine residue of ubiquitin (PubMed:18042044). Essential for viral activation of IRF3 (PubMed:19854139). Mediates polyubiquitination of CYP3A4 (PubMed:19103148).

现货