产品名称
PHLD Rabbit Polyclonal Antibody
蛋白名称
Phosphatidylinositol-glycan-specific phospholipase D (PI-G PLD) (EC 3.1.4.50) (Glycoprotein phospholipase D) (Glycosyl-phosphatidylinositol-specific phospholipase D) (GPI-PLD) (GPI-specific phospholipase D)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
P80108
Human Swissprot Link
https://www.uniprot.org/uniprotkb/P80108/entry
Mouse Swissprot No.
O70362
Mouse Swissprot Link
http://www.uniprot.org/uniprot/O70362
Rat Swissprot Link
http://www.uniprot.org/uniprot/O54941Q8R2H5
免疫原
Synthesized peptide derived from human protein . at AA range: 250-330
特异性
PHLD Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
Many proteins are tethered to the extracellular face of eukaryotic plasma membranes by a glycosylphosphatidylinositol (GPI) anchor. The GPI-anchor is a glycolipid found on many blood cells. The protein encoded by this gene is a GPI degrading enzyme. Glycosylphosphatidylinositol specific phospholipase D1 hydrolyzes the inositol phosphate linkage in proteins anchored by phosphatidylinositol glycans, thereby releasing the attached protein from the plasma membrane. [provided by RefSeq, Jul 2008],
组织表达
Bone marrow,Eye,Liver,Pancreas,Plasma,Serum,
信号通路
Glycosylphosphatidylinositol(GPI)-anchor biosynthesis;
功能
catalytic activity:6-(alpha-D-glucosaminyl)-1-phosphatidyl-1D-myo-inositol + H(2)O = 6-(alpha-D-glucosaminyl)-1D-myo-inositol + phosphatidate.,function:This protein hydrolyzes the inositol phosphate linkage in proteins anchored by phosphatidylinositol glycans (GPI-anchor) thus releasing these proteins from the membrane.,sequence caution:This sequence has numerous of conflicts with the human genome.,similarity:Belongs to the GPLD1 family.,similarity:Contains 4 FG-GAP repeats.,subunit:Monomer .,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
