产品名称
PIGW Rabbit Polyclonal Antibody
蛋白名称
Phosphatidylinositol-glycan biosynthesis class W protein (PIG-W) (EC 2.3.-.-)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
Q7Z7B1
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q7Z7B1/entry
Mouse Swissprot No.
Q8C398
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q8C398
Rat Swissprot Link
http://www.uniprot.org/uniprot/O54941Q7TSN4
免疫原
Synthesized peptide derived from human protein . at AA range: 370-450
特异性
PIGW Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
Glycosylphosphatidylinositol (GPI) is a complex glycolipid that anchors many proteins to the cell surface. PIGW acts in the third step of GPI biosynthesis and acylates the inositol ring of phosphatidylinositol (Murakami et al., 2003 [PubMed 14517336]).[supplied by OMIM, Mar 2008],
细胞定位
Endoplasmic reticulum membrane ; Multi-pass membrane protein .
信号通路
Glycosylphosphatidylinositol(GPI)-anchor biosynthesis;
功能
function:Probable acetyltransferase, which acetylates the inositol ring of phosphatidylinositol during biosynthesis of GPI-anchor. Acetylation during GPI-anchor biosynthesis is not essential for the subsequent mannosylation and is usually removed soon after the attachment of GPIs to proteins.,pathway:Glycolipid biosynthesis; glycosylphosphatidylinositol-anchor biosynthesis.,similarity:Belongs to the PIGW family.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
