产品名称
EXOC3 (7E18) Rabbit Monoclonal Antibody
别名
Exoc3; Sec6; SEC6L1; Sec6p;
纯度
Affinity-chromatography
存储缓冲液
Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% New type preservative N and 0.05% BSA.
Human Swissprot No.
O60645
免疫原
A synthetic peptide of human rSec6
稀释度
WB: 1:1000-1:5000 IHC: 1:20-1:100 ICC/IF: 1:20-1:50 IP: 1:20-1:50
注意事项
EXOC3 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
组织表达
Expressed in epididymis (at protein level).
细胞定位
Cytoplasm {ECO:0000250|UniProtKB:O54921}. Cytoplasm, perinuclear region {ECO:0000250|UniProtKB:O54921}. Cell projection, growth cone {ECO:0000250|UniProtKB:O54921}. Midbody. Golgi apparatus. Cell projection, neuron projection {ECO:0000250|UniProtKB:Q62825}. Note=Perinuclear in undifferentiated cells. Redistributes to growing neurites and growth cones during neuronal differentiation (By similarity). During mitosis, early recruitment to the midbody requires RALA, but not RALB, and EXOC2. In late stages of cytokinesis, localization to the midbody is RALB- dependent (PubMed:18756269). {ECO:0000250|UniProtKB:O54921, ECO:0000269|PubMed:18756269}
功能
Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.
