产品名称
PIN4 (6N9) Rabbit Monoclonal Antibody
别名
EPVH; hEPVH; hPar14; hPar17; Par14; Par17; PIN4;
纯度
Affinity-chromatography
存储缓冲液
Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% New type preservative N and 0.05% BSA.
Human Swissprot No.
Q9Y237
免疫原
A synthetic peptide of human PIN4
稀释度
WB: 1:1000-1:5000 ICC/IF: 1:50 IP: 1:20
注意事项
PIN4 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
组织表达
Isoform 2 is much more stable than isoform 1 (at protein level). Ubiquitous. Isoform 1 and isoform 2 are expressed in kidney, liver, blood vessel, brain, mammary gland, skeletal muscle, small intestine and submandibularis. Isoform 1 transcripts are much more abundant than isoform 2 in each tissue analyzed
细胞定位
[Isoform 1]: Nucleus, nucleolus. Cytoplasm, cytoskeleton, spindle. Cytoplasm. Note=Colocalizes in the nucleolus during interphase and on the spindle apparatus during mitosis with NPM1
功能
Isoform 1 is involved as a ribosomal RNA processing factor in ribosome biogenesis. Binds to tightly bent AT-rich stretches of double- stranded DNA.
