产品名称
SPINK5 / LEKTI (10E19) Rabbit Monoclonal Antibody
别名
LEKTI; NETS; SPINK5; VAKTI;
纯度
Affinity-chromatography
存储缓冲液
Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% New type preservative N and 0.05% BSA.
Human Swissprot No.
Q9NQ38
免疫原
A synthetic peptide of human SPINK5
稀释度
WB: 1:1000-1:5000 ICC/IF: 1:20-1:100
注意事项
SPINK5 / LEKTI Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
组织表达
Highly expressed in the thymus and stratum corneum. Also found in the oral mucosa, parathyroid gland, Bartholin's glands, tonsils, and vaginal epithelium. Very low levels are detected in lung, kidney, and prostate.
功能
Serine protease inhibitor, probably important for the anti- inflammatory and/or antimicrobial protection of mucous epithelia. Contribute to the integrity and protective barrier function of the skin by regulating the activity of defense-activating and desquamation- involved proteases. Inhibits KLK5, it's major target, in a pH-dependent manner. Inhibits KLK7, KLK14 CASP14, and trypsin.
