产品名称
CTP synthase / CTPS (13B6) Rabbit Monoclonal Antibody
别名
CTP synthase 1; CTPS; IMD24;
纯度
Affinity-chromatography
存储缓冲液
Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% New type preservative N and 0.05% BSA.
Human Swissprot No.
P17812
免疫原
A synthetic peptide of human CTP synthase
注意事项
CTP synthase / CTPS Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
细胞定位
Cytoplasm, cytosol. Note=Mainly cytosolic but when active detected in long filamentous structures (PubMed:25223282). Co-localizes with TNK2 in the cytosolic filaments (By similarity). {ECO:0000250|UniProtKB:P70698, ECO:0000269|PubMed:25223282}
功能
This enzyme is involved in the de novo synthesis of CTP, a precursor of DNA, RNA and phospholipids. Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as a source of nitrogen. This enzyme and its product, CTP, play a crucial role in the proliferation of activated lymphocytes and therefore in immunity.
