产品名称
TPTE2 Rabbit Polyclonal Antibody
蛋白名称
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase TPTE2 (EC 3.1.3.67) (Lipid phosphatase TPIP) (TPTE and PTEN homologous inositol lipid phosphatase)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
Q6XPS3
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q6XPS3/entry
免疫原
Synthesized peptide derived from human protein . at AA range: 300-380
特异性
TPTE2 Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
TPIP is a member of a large class of membrane-associated phosphatases with substrate specificity for the 3-position phosphate of inositol phospholipids.[supplied by OMIM, Jul 2002],
组织表达
Isoform 3 is expressed in testis, brain and stomach while isoform 4 seems to be testis-specific.
细胞定位
[Isoform 3]: Endoplasmic reticulum membrane ; Multi-pass membrane protein .; [Isoform 1]: Endoplasmic reticulum membrane ; Multi-pass membrane protein . Golgi apparatus membrane ; Multi-pass membrane protein .; [Isoform 4]: Cytoplasm .
功能
catalytic activity:Phosphatidylinositol 3,4,5-trisphosphate + H(2)O = phosphatidylinositol 4,5-bisphosphate + phosphate.,caution:The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.,similarity:Contains 1 C2 tensin-type domain.,similarity:Contains 1 phosphatase tensin-type domain.,tissue specificity:Isoform 3 is expressed in testis, brain and stomach while isoform 4 seems to be testis-specific.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
