RM6877

LTK (13P18) Rabbit Monoclonal Antibody

Ltk; TYK1;

Affinity-chromatography

常规抗体

LTK

TYK1

WB

Human

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

4058

P29376

WB 1:500~1:2000 IHC 1:50~1:200

92kDa

Rabbit IgG

LTK Antibody is for research use only and not for use in diagnostic or therapeutic procedures.

Expressed in non-hematopoietic cell lines and T- and B-cell lines.

Membrane; Single-pass type I membrane protein.

Receptor with a tyrosine-protein kinase activity. The exact function of this protein is not known. Studies with chimeric proteins (replacing its extracellular region with that of several known growth factor receptors, such as EGFR and CSFIR) demonstrate its ability to promote growth and specifically neurite outgrowth, and cell survival. Signaling appears to involve the PI3 kinase pathway. Involved in regulation of the secretory pathway involving endoplasmic reticulum (ER) export sites (ERESs) and ER to Golgi transport.

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