产品名称
RASSF2 (12M4) Rabbit Monoclonal Antibody
别名
CENP 34; RASFADIN; RASSF2;
纯度
Affinity-chromatography
蛋白名称
CENP-34 {ECO:0000303|PubMed:20813266}, K
存储缓冲液
Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% New type preservative N and 0.05% BSA.
Human Swissprot No.
P50749
免疫原
A synthetic peptide of human RASSF2
注意事项
RASSF2 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
组织表达
Widely expressed with highest levels in brain, placenta, peripheral blood and lung. Frequently down-regulated in lung tumor cell lines.
细胞定位
Nucleus. Cytoplasm. Chromosome, centromere, kinetochore. Note=Translocates to the cytoplasm in the presence of STK3/MST2 AND STK4/MST1
功能
Potential tumor suppressor. Acts as a KRAS-specific effector protein. May promote apoptosis and cell cycle arrest. Stabilizes STK3/MST2 by protecting it from proteasomal degradation.
