产品名称
ING1 (9Q17) Rabbit Monoclonal Antibody
别名
Growth inhibitor ING1; Ing1; Inhibitor of growth 1; mING1h; p24ING1c; p33; p33ING1; p33ING1b; p33ING1c; p37Ing1b; p47; p47ING1a; Tumor suppressor ING1;
纯度
Affinity-chromatography
存储缓冲液
Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% New type preservative N and 0.05% BSA.
Human Swissprot No.
Q9UK53
免疫原
A synthetic peptide of human ING1
注意事项
ING1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
组织表达
Isoform 2 was expressed in all normal tissues and cells examined, as well as in all breast cancer and melanoma cell lines examined. Isoform 3 was expressed in testis, liver, and kidney, weakly expressed in colon and brain and not expressed in breast and cultured melanocytes. Isoform 4 was highly expressed in testis and weakly expressed in brain, but not expressed in breast, colon, kidney, melanocytes, breast cancer or melanoma cell lines
功能
Cooperates with p53/TP53 in the negative regulatory pathway of cell growth by modulating p53-dependent transcriptional activation. Implicated as a tumor suppressor gene.
