产品名称
MPP1 (10G15) Rabbit Monoclonal Antibody
别名
AAG12; DXS552; DXS552E; EMP55; Membrane protein palmitoylated 1; MPP1; MRG1; p55; palmitoylated 1; PEMP;
纯度
Affinity-chromatography
存储缓冲液
Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% New type preservative N and 0.05% BSA.
Human Swissprot No.
Q00013
免疫原
A synthetic peptide of human MPP1
注意事项
MPP1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
细胞定位
Cell membrane; Lipid-anchor. Cell projection, stereocilium {ECO:0000250|UniProtKB:P70290}. Note=Colocalizes with WHRN at stereocilium tip during hair cell development (By similarity) Colocalizes with PALS1 in the retina, at the outer limiting membrane (OLM) (By similarity). Colocalizes with WHRN in the retina, at the outer limiting membrane (OLM), outer plexifirm layer (OPL), basal bodies and at the connecting cilium (CC) (By similarity). Colocalizes with NF2 in non-myelin-forming Schwann cells (PubMed:19144871) {ECO:0000250|UniProtKB:P70290, ECO:0000269|PubMed:19144871}
功能
Essential regulator of neutrophil polarity. Regulates neutrophil polarization by regulating AKT1 phosphorylation through a mechanism that is independent of PIK3CG activity (By similarity).