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FDX1 / ADX (18G16) Rabbit Monoclonal Antibody

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产品基本信息

产品货号
RM6854
产品名称
FDX1 / ADX (18G16) Rabbit Monoclonal Antibody
别名
Adrenodoxin; ADX; FDX; fdx1; Ferredoxin 1; Hepatoredoxin; LOH11CR1D;
纯度
Affinity-chromatography
类别
常规抗体
基因名称
FDX1
蛋白名称
ADX
推荐应用
WB
反应种属
Human,Mouse,Rat
存储缓冲液
Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% New type preservative N and 0.05% BSA.
Human Gene ID
2230
Human Swissprot No.
P10109
免疫原
A synthetic peptide of human Adrenodoxin
稀释度
WB: 1:1000-1:5000
参考分子量
14kDa
预测分子量
19kDa
同种型
Rabbit IgG
注意事项
FDX1 / ADX Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
组织表达
Highest levels in the adrenal gland (at protein level). Also detected in kidney and testis (at protein level)
细胞定位
Mitochondrion matrix
功能
Essential for the synthesis of various steroid hormones (PubMed:20547883, PubMed:21636783). Participates in the reduction of mitochondrial cytochrome P450 for steroidogenesis (PubMed:20547883, PubMed:21636783). Transfers electrons from adrenodoxin reductase to CYP11A1, a cytochrome P450 that catalyzes cholesterol side-chain cleavage (PubMed:20547883, PubMed:21636783). Does not form a ternary complex with adrenodoxin reductase and CYP11A1 but shuttles between the two enzymes to transfer electrons (By similarity).
期货
现货

Western blot analysis of FDX1 / ADX expression in A549 cell lysate.

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