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PLCB1 (4I2) Rabbit Monoclonal Antibody

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产品基本信息

产品货号
RM6828
产品名称
PLCB1 (4I2) Rabbit Monoclonal Antibody
别名
1 phosphatidylinositol 4,5 bisphosphate phosphodiesterase beta 1; 1-phosphatidylinositol 4; EIEE12; Inositoltrisphosphohydrolase; Monophosphatidylinositol phosphodiesterase; Phosphb; Phosphoinositidase C ; Phosphoinositide phospholipase C; Phosphoinositide phospholipase C-beta 1; Phospholipase C beta 1 (phosphoinositide-specific); Phospholipase C I; Phospholipase C-beta-1; Phospholipase C-I; PI PLC; PLC 1; PLC beta 1; PLC-154; PLC-beta-1; PLC-I; PLC154; Plcb; Plcb1; PLCbeta1; Triphosphoinositide phosphodiesterase;
纯度
Affinity-chromatography
类别
常规抗体
基因名称
PLCB1
蛋白名称
KIAA0581
推荐应用
WB
反应种属
Human,Mouse,Rat
存储缓冲液
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
Human Gene ID
23236
Human Swissprot No.
Q9NQ66
稀释度
WB 1:500~1:2000 IHC 1:50~1:200
预测分子量
139kDa
同种型
Rabbit IgG
注意事项
PLCB1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
细胞定位
Nucleus membrane {ECO:0000250|UniProtKB:Q9Z1B3}. Cytoplasm {ECO:0000250|UniProtKB:P10687}. Note=Colocalizes with the adrenergic receptors, ADREN1A and ADREN1B, at the nuclear membrane of cardiac myocytes. {ECO:0000250|UniProtKB:Q9Z1B3}
功能
Catalyzes the hydrolysis of 1-phosphatidylinositol 4,5- bisphosphate into diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) and mediates intracellular signaling downstream of G protein- coupled receptors (PubMed:9188725). Regulates the function of the endothelial barrier.
期货
现货

Western blot analysis of PLCB1 expression in HepG2 cell lysate.

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