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GRK6 (17B2) Rabbit Monoclonal Antibody

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产品基本信息

产品货号
RM6821
产品名称
GRK6 (17B2) Rabbit Monoclonal Antibody
别名
G protein coupled receptor kinase 6; G protein coupled receptor kinase GRK6; G protein-coupled receptor kinase 6; Gprk6; Grk6;
纯度
Affinity-chromatography
类别
常规抗体
基因名称
GRK6
蛋白名称
GPRK6
推荐应用
WB
反应种属
Human,Mouse
存储缓冲液
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
Human Gene ID
2870
Human Swissprot No.
P43250
稀释度
WB 1:500~1:2000
预测分子量
66kDa
同种型
Rabbit IgG
注意事项
GRK6 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
组织表达
Widely expressed..
细胞定位
Membrane; Lipid-anchor.
功能
Specifically phosphorylates the activated forms of G protein- coupled receptors. Such receptor phosphorylation initiates beta- arrestin-mediated receptor desensitization, internalization, and signaling events leading to their desensitization. Seems to be involved in the desensitization of D2-like dopamine receptors in striatum and chemokine receptor CXCR4 which is critical for CXCL12-induced cell chemotaxis (By similarity). Phosphorylates rhodopsin (RHO) (in vitro) and a non G-protein-coupled receptor: LRP6 during Wnt signaling (in vitro).
期货
现货

Western blot analysis of GRK6 expression in Ramos cell lysate.

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