RM6816

UFM1 (3Y5) Rabbit Monoclonal Antibody

BM002; Chromosome 13 open reading frame 20; Ubiquitin-fold modifier 1; UFM1;

Affinity-chromatography

常规抗体

UFM1 {ECO:0000303|PubMed:15071506, ECO:0000312|HGNC:HGNC:20597}

WB

Human,Mouse,Rat

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% New type preservative N and 0.05% BSA.

51569

P61960

A synthetic peptide of human UFM1

WB: 1:1000 IHC: 1:50-1:200 IP: 1:20

9kDa

9kDa

Rabbit IgG

UFM1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.

Nucleus. Cytoplasm

Ubiquitin-like modifier which can be covalently attached via an isopeptide bond to lysine residues of substrate proteins as a monomer or a lysine-linked polymer (PubMed:15071506, PubMed:20018847, PubMed:29868776, PubMed:27653677). The so-called ufmylation, requires the UFM1-activating E1 enzyme UBA5, the UFM1-conjugating E2 enzyme UFC1, and the UFM1-ligase E3 enzyme UFL1 (PubMed:15071506, PubMed:20018847, PubMed:29868776, PubMed:27653677). Ufmylation is involved in reticulophagy (also called ER-phagy) induced in response to endoplasmic reticulum stress (PubMed:32160526). Ufmylation of TRIP4 regulates nuclear receptors-mediated transcription (PubMed:25219498).

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