产品名称
MAP3K4 (6F14) Rabbit Monoclonal Antibody
别名
MAP three kinase 1; MAP/ERK kinase kinase 4; MAP3K4; MAPK/ERK kinase kinase 4; MAPKKK4; MEK kinase 4; MEKK4; Mitogen-activated protein kinase kinase kinase 4; MTK1; predicted protein of HQ0412; PRO0412;
纯度
Affinity-chromatography
蛋白名称
KIAA0213, MAPKKK4, MEKK4, MTK1
存储缓冲液
Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% New type preservative N and 0.05% BSA.
Human Swissprot No.
Q9Y6R4
免疫原
A synthetic peptide of human MAP3K4
稀释度
WB: 1:1000 IHC: 1:20 ICC/IF: 1:50 FC: 1:20
注意事项
MAP3K4 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
组织表达
Expressed at high levels in heart, placenta, skeletal muscle and pancreas, and at lower levels in other tissues
细胞定位
Cytoplasm, perinuclear region. Note=Localized in perinuclear vesicular-like structures, probably Golgi-associated vesicles.
功能
Component of a protein kinase signal transduction cascade. Activates the CSBP2, P38 and JNK MAPK pathways, but not the ERK pathway. Specifically phosphorylates and activates MAP2K4 and MAP2K6.
