产品名称
Cytokeratin 19 (5X19) Rabbit Monoclonal Antibody
别名
CK19; Cytokeratin 19; K19; K1CS; Keratin 19; Keratin type I 40kD; Keratin type I cytoskeletal 19; KRT19;
纯度
Affinity-chromatography
存储缓冲液
Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% New type preservative N and 0.05% BSA.
Human Swissprot No.
P08727
免疫原
A synthetic peptide of human Cytokeratin 19
稀释度
WB: 1:2000-1:10000 IHC: 1:20-1:100 ICC/IF: 1:20-1:50 FC: 1:20 IP: 1:20
注意事项
Cytokeratin 19 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
组织表达
Expressed in a defined zone of basal keratinocytes in the deep outer root sheath of hair follicles. Also observed in sweat gland and mammary gland ductal and secretory cells, bile ducts, gastrointestinal tract, bladder urothelium, oral epithelia, esophagus, ectocervical epithelium (at protein level). Expressed in epidermal basal cells, in nipple epidermis and a defined region of the hair follicle. Also seen in a subset of vascular wall cells in both the veins and artery of human umbilical cord, and in umbilical cord vascular smooth muscle. Observed in muscle fibers accumulating in the costameres of myoplasm at the sarcolemma in structures that contain dystrophin and spectrin.
功能
Involved in the organization of myofibers. Together with KRT8, helps to link the contractile apparatus to dystrophin at the costameres of striated muscle.
