产品名称
Adiponectin (18K12) Rabbit Monoclonal Antibody
别名
30 kDa adipocyte complement related protein; ACDC; ACRP30; Adipocyte; Adiponectin; Adipoq; Adipose most abundant gene transcript 1; Adipose specific collagen like factor; ADIPQTL1; ADPN; APM1; GBP28; Gelatin binding protein; Gelatin binding protein 28;
纯度
Affinity-chromatography
存储缓冲液
Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% New type preservative N and 0.05% BSA.
Human Swissprot No.
Q15848
免疫原
A synthetic peptide of human Adiponectin
稀释度
WB: 1:1000-1:5000 IP: 1:20
注意事项
Adiponectin Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
组织表达
Synthesized exclusively by adipocytes and secreted into plasma.
功能
Important adipokine involved in the control of fat metabolism and insulin sensitivity, with direct anti-diabetic, anti-atherogenic and anti-inflammatory activities. Stimulates AMPK phosphorylation and activation in the liver and the skeletal muscle, enhancing glucose utilization and fatty-acid combustion. Antagonizes TNF-alpha by negatively regulating its expression in various tissues such as liver and macrophages, and also by counteracting its effects. Inhibits endothelial NF-kappa-B signaling through a cAMP-dependent pathway. May play a role in cell growth, angiogenesis and tissue remodeling by binding and sequestering various growth factors with distinct binding affinities, depending on the type of complex, LMW, MMW or HMW.