产品名称
P2Y12 (3U6) Rabbit Monoclonal Antibody
别名
ADP glucose receptor; ADPGR; BDPLT8; HORK3; P2RY12; P2Y purinoceptor 12; P2Y12; P2Y12 platelet ADP receptor; Platelet ADP receptor; Purinergic receptor P2RY12; Purinergic receptor P2Y12; SP1999;
纯度
Affinity-chromatography
存储缓冲液
Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% New type preservative N and 0.05% BSA.
Human Swissprot No.
Q9H244
免疫原
A synthetic peptide of human P2Y12
注意事项
P2Y12 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
组织表达
Highly expressed in the platelets, lower levels in the brain. Lowest levels in the lung, appendix, pituitary and adrenal gland. Expressed in the spinal cord and in the fetal brain
细胞定位
Cell membrane; Multi-pass membrane protein
功能
Receptor for ADP and ATP coupled to G-proteins that inhibit the adenylyl cyclase second messenger system. Not activated by UDP and UTP. Required for normal platelet aggregation and blood coagulation.